Welcome to the Jiang Lab

 We are recruiting Postdocs, Graduate students, Visiting scholars, and Technicians. Please email us if you are interested.

The Jiang lab at the UNC HIV Cure Center and BCBP aims to understand the molecular mechanisms of stable HIV reservoirs in the resident immune cells of people with HIV (PWH). We focus on how HIV transcription is regulated during active HIV transcription and HIV latency in both peripheral compartments, such as PBMCs and the spleen, and the central nervous system. The traditional biochemistry, molecular biology, and virology approaches are used for these studies, while many modern omics analyses are actively applied to address the extremely challenging questions of HIV cure, including quantitative proteomics, sc/snRNA-seq, ATAC-seq, and CUT&RUN. The goal is to translate our understanding of HIV persistence into therapeutic interventions for a cure for HIV. We welcome graduate students and postdocs who want to be trained in epigenetics, signaling transduction, immunology/virology of HIV, and neurobiology/neuroinflammation with advanced models of HIV infection and latency.

The Jiang Lab is actively supported by the National Institute of Mental Health (NIMH) through grant R01MH136852, the National Institute of Allergy and Infectious Diseases (NIAID) through grant R01AI186609, and the CARE Program (UM1AI164567).